Effects of Testosterone on Mixed-Muscle Protein Synthesis and Proteome Dynamics During Energy Deficit.
Emily E HowardMahalakshmi ShankaranWillian J EvansClaire E BerrymanLee M MargolisHarris R LiebermanJ Philip KarlAndrew J YoungMonty A MontanoMarcy D MatthewsAlec BizieffEdna NyangaoHussein MohammedMelissa N HarrisMarc K HellersteinJennifer C RoodStefan M PasiakosPublished in: The Journal of clinical endocrinology and metabolism (2022)
The high proportion of individual proteins with greater FSR in TEST than PLA at Post suggests exogenous testosterone exerted a delayed but broad stimulatory effect on synthesis rates across the muscle proteome during energy deficit, resulting in muscle mass accretion during subsequent recovery.
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