Anti-angiogenic drug loaded liposomes: Nanotherapy for early atherosclerotic lesions in mice.

Isabel PontAracely Calatayud-PascualAlicia López-CastellanoElena P AlbeldaEnrique García-EspañaLuis Martí-BonmatíJuan C FriasM Teresa Albelda

Published in: PloS one (2018)

Fumagillin-loaded liposomes were injected into ApoE-KO mice. The animals were divided into several groups to test the efficacy of this anti-angiogenic drug for early treatment of atherosclerotic lesions. Statistical analysis of the lesions revealed a decrease in the lesion size after 5 weeks of treatment.

Keyphrases

drug delivery
cancer therapy
drug release
single cell
combination therapy
skeletal muscle
adverse drug
smoking cessation