Quantitative SARS-CoV-2 RT-PCR and Bronchoalveolar Cytokine Concentrations Redefine the COVID-19 Phenotypes in Critically Ill Patients.

Christina Vazquez GuillametRodrigo Vazquez GuillametAshraf RjobDaniel ReynoldsBijal ParikhVladimir DespotovicDerek E ByersAli H EllebedyMarin H KollefPhilip A Mudd

Published in: Journal of intensive care medicine (2024)

We identified a unique group of critically ill subjects with COVID-19 ARDS who exhibit hypoinflammatory responses but high viral loads in the lower airways. These clusters may warrant different treatment approaches to improve clinical outcomes.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
cystic fibrosis
acute respiratory distress syndrome
high resolution
mechanical ventilation
real time pcr
replacement therapy