Liquid biopsy in peritoneal fluid and plasma as a prognostic factor in advanced colorectal and appendiceal tumors after complete cytoreduction and hyperthermic intraperitoneal chemotherapy.

Irene López-RojoSusana Olmedillas-LópezPedro Villarejo CamposVíctor Domínguez PrietoJavier Barambio BuendíaDelia Cortés GuiralMariano García-ArranzDamián García-Olmo

Published in: Therapeutic advances in medical oncology (2020)

Treatment with CC-HIPEC does not always neutralize ctDNA in peritoneal fluid, and its persistence after treatment may predict adverse outcome. Despite being a proof of concept, an adequate correlation between liquid biopsy in plasma and peritoneal fluid with both systemic and peritoneal relapse has been observed.

Keyphrases

prognostic factors
ultrasound guided
ionic liquid
squamous cell carcinoma
emergency department
locally advanced
radiation therapy
rectal cancer
smoking cessation
electronic health record