Clinical Spectrum of Long COVID: Effects on Female Reproductive Health.
Syeda MahamMee-Sup YoonPublished in: Viruses (2024)
The COVID-19 pandemic caused by SARS-CoV-2 has presented numerous health challenges, including long-term COVID, which affects female reproductive health. This review consolidates the current research on the impact of SARS-CoV-2 on the menstrual cycle, ovarian function, fertility, and overall gynecological health. This study emphasizes the role of angiotensin-converting enzyme receptors in viral entry and the subsequent tissue-specific pathological effects. It also explores the potential influence of long COVID on hormonal balance and immune responses, contributing to menstrual irregularities and impaired ovarian function. The findings indicate a higher prevalence of long-term COVID-19 among women, highlighting the substantial implications for reproductive health and the need for sex-sensitive longitudinal studies. Enhanced surveillance and targeted research are essential to develop effective interventions that prioritize women's reproductive well-being following SARS-CoV-2 infection. This review advocates for a sex-informed approach to ongoing COVID-19 research and healthcare strategies, aiming to provide up-to-date and pertinent data for healthcare providers and the general public, ultimately improving outcomes for females affected by long COVID.
Keyphrases
- sars cov
- healthcare
- coronavirus disease
- respiratory syndrome coronavirus
- public health
- mental health
- immune response
- angiotensin converting enzyme
- physical activity
- angiotensin ii
- toll like receptor
- machine learning
- risk factors
- health information
- electronic health record
- artificial intelligence
- inflammatory response
- health insurance