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Heterogeneous EGFR, CDK4, MDM4, and PDGFRA Gene Expression Profiles in Primary GBM: No Association with Patient Survival.

María González-TablasDaniel ArandiaMaría Jara-AcevedoÁlvaro Otero RodriguezAna-Luisa VitalCarlos PrietoNerea González-GarciaAna Belén Nieto-LibreroHerminio TaoDaniel PascualLaura RuizPablo SousaM Purificación Galindo-VillardónAlberto OrfaoMaria Dolores Tabernero Redondo
Published in: Cancers (2020)
Overall, none of the gene expression profiles and/or intragenic EGFR deletions showed a significant impact on overall survival of GBM supporting the notion that other still unraveled features of the disease might play a more relevant prognostic role in GBM.
Keyphrases
  • small cell lung cancer
  • epidermal growth factor receptor
  • tyrosine kinase
  • copy number
  • genome wide
  • free survival
  • case report
  • cell cycle
  • transcription factor