A practical guide to methods controlling false discoveries in computational biology.
Keegan KorthauerPatrick K KimesClaire DuvalletAlejandro ReyesAyshwarya SubramanianMingxiang TengChinmay ShuklaEric J AlmStephanie C HicksPublished in: Genome biology (2019)
Modern FDR methods that use an informative covariate provide advantages over classic FDR-controlling procedures, with the relative gain dependent on the application and informativeness of available covariates. We present our findings as a practical guide and provide recommendations to aid researchers in their choice of methods to correct for false discoveries.
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