Association of circulating SLAMF7+Tfh1 cells with IgG4 levels in patients with IgG4-related disease.

Kazuhiko HigashiokaYuri OtaTakashi MaeharaMasafumi MoriyamaMasahiro AyanoHiroki MitomaMitsuteru AkahoshiYojiro ArinobuTakahiko HoriuchiSeiji NakamuraKoichi AkashiHiroaki Niiro

Published in: BMC immunology (2020)

Together, these results suggest that circulating SLAMF7+ Tfh1 cells, along with Tfh2 cells, play a pathologic role in IgG4 production in IgG4-RD.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
cell death
radiation therapy
neoadjuvant chemotherapy