Hydroxychloroquine in lupus pregnancy and risk of preeclampsia.

Amadeia RectorIvana MarićYashaar ChaichianEliza ChakravartyMiranda CantuMichael H WeismanGary M ShawMaurice DruzinJulia F Simard

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

Using a large insurance-based database, we did not observe a decreased risk of preeclampsia associated with HCQ use in pregnancy, although we cannot rule out residual and unmeasured confounding and misclassification. Further studies leveraging large population-based data and prospective collection could characterize how HCQ influences preeclampsia risk in SLE pregnancy and among persons at greater risk of hypertensive disorders of pregnancy.

Keyphrases

pregnancy outcomes
preterm birth
early onset
systemic lupus erythematosus
pregnant women
blood pressure
disease activity
emergency department
big data
adverse drug
long term care
drug induced