Novel siRNA formulation to effectively knockdown mutant p53 in osteosarcoma.

Anup K KunduSwathi V IyerSruti ChandraAmit S AdhikariTomoo IwakumaTarun K Mandal

Published in: PloS one (2017)

This study warrants a future evaluation of this formulation for gene silencing efficiency of mutant p53 in tissue culture and animal models for the treatment of osteosarcoma.

Keyphrases

drug delivery
wild type
cancer therapy
combination therapy
hyaluronic acid