Frequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling.

Mizunori YaegashiTakeshi IwayaNoriyuki SasakiMasashi FujitaZhenlin JuDoris SiwakTsuyoshi HachiyaKei SatoFumitaka EndoToshimoto KimuraKoki OtsukaRyo SugimotoTamotsu SugaiLance LiottaYiling LuGordon B MillsHidewaki NakagawaSatoshi S Nishizuka

Published in: British journal of cancer (2021)

A single biopsy is sufficient to develop custom dPCR probes for monitoring tumour burden in most CRC patients. However, it may not be effective for those with hypermutated tumours.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
small molecule
peritoneal dialysis
single molecule
prognostic factors
ultrasound guided
risk factors
living cells
photodynamic therapy
patient reported
circulating tumor cells