A single dose of exercise stimulates skeletal muscle mitochondrial plasticity in myotonic dystrophy type 1.
Andrew I MikhailAlexander MantaSean Y NgAislin K OsborneStephanie R MattinaMark R MackieVladimir LjubicicPublished in: Acta physiologica (Oxford, England) (2023)
Collectively, our data indicate that mitochondrial dynamics and turnover processes in DM1 skeletal muscle are initiated with a single dose of exercise, which may underlie the adaptive benefits previously documented in DM1 mice and patients.
Keyphrases
- skeletal muscle
- end stage renal disease
- oxidative stress
- high intensity
- insulin resistance
- newly diagnosed
- physical activity
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- type diabetes
- adipose tissue
- big data
- patient reported outcomes
- machine learning
- deep learning
- postmenopausal women
- artificial intelligence