Targeting miR-126 disrupts maintenance of myelodysplastic syndrome stem and progenitor cells.
Huafeng WangJie SunBin ZhangDandan ZhaoHongyan TongHerman WuXia LiYingwan LuoDan DongYiyi YaoTinisha McDonaldAnthony S SteinMonzr M Al MalkiFlavia PichiorriNadia CarlessoYa-Huei KuoGuido MarcucciLing LiJie JinPublished in: Clinical and translational medicine (2022)
MiR-126 plays crucial roles in MDS HSPC maintenance. Therapeutic targeting of miR-126 is a potentially novel approach in MDS.