8-Hydroxy-2’-deoxyguanosine as a biomarker of oxidative stress in acute exacerbation of chronic obstructive pulmonary disease
Xing LıuKaili DengSixia ChenYunshi ZhangJing YaoXiaoqin WengYang ZhangTianming GaoGanzhu FengPublished in: Turkish journal of medical sciences (2019)
8-OHdG is associated with spirometric severity, symptomatic severity, exacerbation risk, and inflammatory biomarkers in AECOPD patients, suggesting it as a promising biomarker for reflecting disease severity and guiding the choice of optimal therapeutic decision.
Keyphrases
- oxidative stress
- chronic obstructive pulmonary disease
- end stage renal disease
- respiratory failure
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- liver failure
- prognostic factors
- dna damage
- patient reported outcomes
- ischemia reperfusion injury
- intensive care unit
- drug induced
- endoplasmic reticulum stress
- patient reported
- heat shock protein