POEMS syndrome presents with a distended abdomen: A case report.
Wenshu WangGui-Bin YangPublished in: The Journal of international medical research (2023)
POEMS syndrome is a rare, serious, multisystem disorder and its diagnosis is frequently missed due to its varied clinical presentation. We report here, a 69-year-old woman with initial complaints of distended abdomen, who was misdiagnosed with tuberculosis but failed anti-tuberculosis treatment. Further examinations showed peripheral neuropathy, monoclonal plasma cell disease, sclerotic bone lesions, an elevated serum vascular endothelial growth factor (VEGF) concentration, lymph node hyperplasia, endocrine abnormalities, and skin hyperpigmentation. A diagnosis of POEMS syndrome was made and the patient responded to lenalidomide-based chemotherapy.
Keyphrases
- vascular endothelial growth factor
- lymph node
- case report
- mycobacterium tuberculosis
- endothelial cells
- multiple myeloma
- hiv aids
- pulmonary tuberculosis
- stem cells
- emergency department
- single cell
- neoadjuvant chemotherapy
- bone mineral density
- cell therapy
- mesenchymal stem cells
- low dose
- radiation therapy
- early stage
- bone marrow