Primary sclerosing cholangitis causally affects kidney function decline: A Mendelian randomization study.
Jeong Min ChoJung Hun KohSeong Geun KimSoojin LeeYaerim KimSemin ChoKwangsoo KimYong Chul KimSeung Seok HanHajeong LeeJung Pyo LeeKwon Wook JooChun Soo LimYon Su KimDong Ki KimSehoon ParkPublished in: Journal of gastroenterology and hepatology (2023)
Our study demonstrates that genetically predicted PSC is causally associated with kidney function impairment. Further studies are warranted to identify the underlying mechanisms.
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