Multi-omics integration reveals a core network involved in host defence and hyperkeratinization in psoriasis.
Chuanjian LuEmmerik F A LeijtenMichel Olde NordkampGuangjuan ZhengJuliëtte PouwWeiyang TaoSarita HartgringDeepak BalakRianne RijkenRunyue HuangTimothy RadstakeChuan-Jian LuAridaman PanditPublished in: Clinical and translational medicine (2022)
We identified a core gene network that associated with local disease severity and microbiome composition, involved in the inflammation and hyperkeratinization in psoriatic skin.