An indicator displacement assay recognizes enantiomers of chiral carboxylates.

Sara Sheykhi Lorenzo MoscaJohnathon M DurgalaPavel Anzenbacher

Published in: Chemical communications (Cambridge, England) (2019)

Two chiral copper(ii)-based receptors-[CuRRL]2+ and [CuSSL]2+-in conjuction with the fluorescent indicator coumarin 343 were used to establish an enantioselective indicator displacement assay (eIDA) for the determination of the enantiomeric composition of chiral carboxylates such as ibuprofen, naproxen and atorvastatin.

Keyphrases

capillary electrophoresis
mass spectrometry
high throughput
ionic liquid
quantum dots
living cells
liquid chromatography
high resolution
single cell
oxide nanoparticles
label free