A One-Pot Procedure for the Synthesis of "Click-Ready" Triazoles from Ketones.

A practical, straightforward, and highly regioselective Zn(OAc)2-mediated method toward propargyl triazoles has been developed for the first time from commercially available enolizable ketones and propargyl amine. Postfunctionalization of this triazole leads to unique N- and C-linked bis-triazoles in excellent yields.