The novel drug candidate VOMG kills Mycobacterium abscessus and other pathogens by inhibiting cell division.

Giulia DegiacomiLaurent R ChiarelliOlga RiabovaNicola Ivan LoréLara Muñoz-MuñozDeborah RecchiaGiovanni StelitanoUmberto PostiglioneFabio SaliuAnna GriegoViola Camilla ScoffoneElena KazakovaEdoardo ScarpaJosé Manuel Ezquerra-AznárezAlessandro StamillaSilvia BuroniEnrico TortoliLoris RizzelloDavide SasseraSantiago Ramón-GarcíaDaniela Maria CirilloVadim MakarovMaria Rosalia Pasca

Published in: International journal of antimicrobial agents (2024)

VOMG is a new drug-like molecule active against M. abscessus, inhibiting cell division with broad-spectrum activity against other microbial pathogens.

Keyphrases

single cell
cell therapy
signaling pathway
gram negative
mycobacterium tuberculosis
antimicrobial resistance
multidrug resistant