Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes.

Published in: The EPMA journal (2020)

Those findings provided the potential targeted lncRNA-EIF4A3-mRNA pathways of ivermectin in OC, and constructed the effective prognostic model, which benefits discovery of novel mechanism of ivermectin to suppress ovarian cancer cells, and the ivermectin-related molecule-panel changes benefit for its personalized drug therapy and prognostic assessment towards its predictive, preventive, and personalized medicine (PPPM) in OCs.

Keyphrases

drug administration
long non coding rna
small molecule
long noncoding rna
wastewater treatment
drug induced
cancer therapy
emergency department
bone marrow
mesenchymal stem cells
climate change
trypanosoma cruzi