Bone erosions by MRI in first-degree relatives of patients with RA: an exploratory study.
David Vega MoralesMaría Del Carmen Larios-ForteLorena Perez-BarbosaJorge Antonio Esquivel-ValerioMario Alberto Garza-ElizondoCassandra Michelle Skinner-TaylorBrenda Roxana Vázquez-FuentesDiana Elsa Flores-AlvaradoMiguel Ángel Villarreal-AlarcónIvan de Jesus Hernandez-GalarzaLuis Iván Lozano-PlataMartha Mariana Castañeda-MartínezDiana Daniela Castañeda-MartínezPablo Herrera-SandateJesus A Cardenas-de la GarzaDionicio Ángel Galarza-DelgadoPublished in: Clinical rheumatology (2022)
• First-degree relatives (FDR) of rheumatoid arthritis (RA) patients with positive serology and joint symptoms constitute a select subpopulation of individuals with an increased risk of developing RA. • Magnetic resonance imaging (MRI) of FDR shows a high prevalence of bone erosions of any grade, grade ≥ 2 erosions, and synovitis. • MRI might be helpful in FDR of RA patients to screen for the presence of RA-specific erosions or clinically undetectable synovitis.
Keyphrases
- rheumatoid arthritis
- magnetic resonance imaging
- disease activity
- contrast enhanced
- ankylosing spondylitis
- diffusion weighted imaging
- end stage renal disease
- interstitial lung disease
- bone mineral density
- computed tomography
- systemic lupus erythematosus
- ejection fraction
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- magnetic resonance
- systemic sclerosis
- bone loss
- postmenopausal women
- bone regeneration
- high throughput
- single cell
- body composition
- idiopathic pulmonary fibrosis