NDRG1 Signaling Is Essential for Endothelial Inflammation and Vascular Remodeling.
Guanxin ZhangQing QinChen ZhangXiaobo SunKyosuke KazamaBing YiFang ChengZhi-Fu GuoJianxin SunPublished in: Circulation research (2022)
Our results for the first time identify NDRG1 as a critical mediator implicated in regulating endothelial inflammation, thrombotic responses, and vascular remodeling, and suggest that inhibition of NDRG1 may represent a novel therapeutic strategy for inflammatory vascular diseases, such as atherothrombosis and restenosis.
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