Preclinical study of simultaneous pharmacokinetic and pharmacodynamic herb-drug interactions between Yin-Chen-Hao-Tang and spironolactone.

Published in: BMC complementary medicine and therapies (2020)

Herb-drug pharmacokinetic and pharmacodynamic interactions between YCHT and spironolactone were observed in the study. The herb-drug interaction that appeared with a single dose of spironolactone should be considered when patients are being treated with a continuous administration of this drug.

Keyphrases

end stage renal disease
adverse drug
ejection fraction
chronic kidney disease
stem cells
drug induced
mesenchymal stem cells
prognostic factors
patient reported outcomes
cell therapy