Molecular characteristics of low-grade serous carcinoma in effusions.

Delfim DoutelBen DavidsonIna Kathrine Nitschke PettersenAnnette Torgunrud

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)

The molecular alterations in LGSCs in serous effusions are consistent with those found in solid tumours, with frequent alterations in the mitogen-activated protein kinase pathway. Mutations in LGSC may be a marker of better outcomes.

Keyphrases

high grade
low grade
single molecule
tyrosine kinase
protein kinase
metabolic syndrome