Adherence to a topical moisturizing preparation for regorafenib-related hand-foot skin reaction.

Junya SatoHiroshi IshikawaSatoshi HamauchiYuki YamawakiKeita MoriYoshio KiyoharaShusuke YoshikawaKentaro YamazakiHirofumi YasuiMichihiro Shino

Published in: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners (2019)

The results suggest that adherence decreases in patients with working. The relative dose intensity of regorafenib decreased when adherence to topical moisturizing ointments decreased. Severe hand-foot skin reaction could be associated with adherence. Patients consciously might not apply the ointment when hand-foot skin reaction did not become severe. It will be problematic for medical personnel to motivate patients for improving adherence to the use of moisturizing ointments.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
wound healing
healthcare
chronic kidney disease
prognostic factors
glycemic control
early onset
peritoneal dialysis
type diabetes
patient reported outcomes
high resolution
molecularly imprinted