JMJD2A sensitizes gastric cancer to chemotherapy by cooperating with CCDC8.

Tadahiko NakagawaYasushi SatoToshihito TanahashiYasuhiro MitsuiYoshifumi KidaYasuteru FujinoMisato HirataShinji KitamuraHiroshi MiyamotoKoichi OkamotoNaoki MugurumaYoshimi BandoTetsuji Takayama

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2019)

Our results indicate that JMJD2A is a novel epigenetic factor affecting GC chemotherapeutic susceptibility, and JMJD2A/CCDC8 is a potential GC therapeutic target.

Keyphrases

dna methylation
gas chromatography
locally advanced
induced apoptosis
squamous cell carcinoma
human health
mass spectrometry
risk assessment
endoplasmic reticulum stress
simultaneous determination