Identification of the asymptomatic Plasmodium falciparum and Plasmodium vivax gametocyte reservoir under different transmission intensities.
Cristian KoepfliWang NguitragoolAnne Cristine Gomes de AlmeidaAndrea KuehnAndreea WaltmannJohanna Helena KattenbergMaria Ome-KaiusPatricia RarauThomas ObadiaJames W KazuraWuelton MonteiroAndrew W DarcyLyndes WiniSozinho AcácioIngrid FelgerJetsumon SattabongkotLeanne J RobinsonMarcus LacerdaIvo MuellerPublished in: PLoS neglected tropical diseases (2021)
Interventions to reduce human-to-mosquito malaria transmission in moderate-high endemicity settings will have the greatest impact when children are targeted. In contrast, all age groups need to be included in control activities in low endemicity settings to achieve elimination. Detection of infections by light microscopy is a valuable tool to identify asymptomatic blood stage infections that likely contribute most to ongoing transmission at the time of sampling.