DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients.

Alfonso RubinoClaudio D'AddarioMartina Di BartolomeoEnrico Michele SalamoneNicoletta LocuratoloFrancesco FattappostaNicola VanacoreEsterina Pascale

Published in: Acta neurologica Scandinavica (2020)

Our results do seem to suggest that the methylation level of CpG5 is different between PD patients and controls. Moreover, this methylation level for CpG5 may be associated also with the stage of disease.

Keyphrases

dna methylation
end stage renal disease
genome wide
ejection fraction
newly diagnosed
chronic kidney disease
gene expression
prognostic factors
transcription factor
patient reported