Letter to the editor: fasting decreases expression of microRNAs linked to endothelial pathophysiology in mononuclear cells of healthy subjects.
Denise HoneycuttArno Schmidt-TrucksässMarijke BrinkNicolle KränkelJulia M KröpflPublished in: Apoptosis : an international journal on programmed cell death (2024)
This study explores how 14-15 h fasting or acute exercise affects immune cell epigenetics, specifically focusing on miRNAs in mononuclear cells. Findings suggest fasting significantly impacts microRNAs associated with endothelial metabolism compared to exercise, but does not directly connect these changes to cell apoptosis or autophagy. This enhances comprehension of cellular self-consumption under health-promoting interventions.
Keyphrases
- induced apoptosis
- cell cycle arrest
- blood glucose
- endoplasmic reticulum stress
- physical activity
- insulin resistance
- cell death
- endothelial cells
- high intensity
- healthcare
- signaling pathway
- public health
- peripheral blood
- mental health
- resistance training
- cell proliferation
- liver failure
- metabolic syndrome
- blood pressure
- intensive care unit
- health information
- social media
- aortic dissection
- weight loss