Neurological manifestations in patients and disease carriers in an Italian family with osteosclerosis.

Francesco BonoLaura RapisardaCaterina BombardieriMonica GagliardiRadha ProcopioGiulio DemonteFederico TostoPietro A BrunoAntonio GambardellaGrazia Annesi

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

Multiple cranial neuropathies and headache in children, while severe chronic headache and sleep disturbances in adults, are the neurological manifestations of the first Italian family with osteosclerosis. It is reasonable to extend neurological and neuroimaging evaluation to gene carriers as well.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
cerebral ischemia
early onset
gene expression
genome wide
sleep quality
drug induced
genome wide identification