PGRN is involved in macrophage M2 polarization regulation through TNFR2 in periodontitis.
Liguo ZhangFujiao NieJingjing ZhaoShutong LiWenchuan LiuHongmei GuoPi-Shan YangPublished in: Journal of translational medicine (2024)
In summary, PGRN promotes macrophage M2 polarization through binding to TNFR2 in both pro- and anti-inflammatory periodontal microenvironments.
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