A better understanding of basic science may help our management of LUTS/LUTD in older persons with nocturnal polyuria and nocturia: ICI-RS 2024.
Anthony J KanaiKarel EveraertApostolos ApostolidisChristopher Henry FryPradeep TyagiAndries Van HueleBahareh VahabiWendy F BowerAlan WeinPaul AbramsPublished in: Neurourology and urodynamics (2024)
Pre-proAVP is present in human/rodent bladders and may be involved in water reabsorption from bladder that prevents the sensation of fullness for uninterrupted sleep in healthy adults. The mechanism of action of AVP in the CNS was discussed, as was electrolyte/water transport across the bladder, the basis for dAVP toxicity, and feasibility of urine biomarkers to identify nocturia/LUTD with neurological diseases.
Keyphrases
- lower urinary tract symptoms
- benign prostatic hyperplasia
- spinal cord injury
- endothelial cells
- physical activity
- sleep quality
- public health
- blood pressure
- obstructive sleep apnea
- urinary tract
- ionic liquid
- oxidative stress
- blood brain barrier
- middle aged
- community dwelling
- depressive symptoms
- atrial fibrillation
- direct oral anticoagulants
- ion batteries