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Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studies.

Michael P MackleyBenjamin FletcherMichael ParkerHugh WatkinsElizabeth Ormondroyd
Published in: Genetics in medicine : official journal of the American College of Medical Genetics (2016)
This review suggests that bidirectional interaction during consent might best facilitate informed decision making about SF and that dynamic forms of consent, allowing for changing preferences, should be considered. Research exploring views from wider perspectives and from recipients who have received SF is critical if evidence-based policies are to be achieved.Genet Med 19 3, 283-293.
Keyphrases
  • decision making
  • public health
  • high resolution
  • systematic review
  • case control
  • kidney transplantation
  • mass spectrometry