Low Detection Rate of Bordetella pertussis Using the BioFire FilmArray Respiratory Panel 2plus.
Sophie GuillotAssaf MizrahiNathalie ArmatysLaureen ChatAlban Le MonnierSylvain BrisseJulie ToubianaPublished in: Open forum infectious diseases (2020)
Syndromic respiratory panels are increasingly used worldwide. Their performance for detection of Bordetella pertussis needs to be evaluated. We found that the FilmArray Respiratory Panel 2plus (RP2+) assay, which uses the pertussis toxin promoter target for B. pertussis, can only detect highly charged samples. Negative RP2+ results should not be interpreted as an absence of B. pertussis in clinical samples.