Reduced Mitochondrial Protein Translation Promotes Cardiomyocyte Proliferation and Heart Regeneration.
Feng GaoTian LiangYao Wei LuLinbin PuXuyang FuXiaoxuan DongTingting HongFeng ZhangNing LiuYuxia ZhouHongkun WangPing LiangYuxuan GuoHong YuWei ZhuXinyang HuHong ChenBin ZhouWilliam T PuJohn D MablyWangxing HuDa-Zhi WangJinghai ChenPublished in: Circulation (2023)
These data highlight a critical role for MRPS5/ATF4 in cardiomyocytes and an exciting new avenue of study for therapies to treat myocardial injury.