Exploring the nasopharyngeal microbiota composition in infants with whooping cough: A test-negative case-control study.

Muntsa RocafortDesiree HenaresPedro BrotonsIrene BarrabeigCristian LaunesLore MerdrignacMarta ValencianoÁngela DomínguezPere GodoyCarmen Muñoz-Almagro

Published in: PloS one (2021)

This study supports the usefulness of 16S rRNA gene sequencing for improved sensitivity on pertussis diagnosis compared to real-time PCR and to understand other microbial changes occurring in the nasopharynx in children <1 year old with suspected whooping cough compared to healthy controls.

Keyphrases

real time pcr
young adults
microbial community
pulmonary embolism
single cell
genome wide
copy number
gene expression
transcription factor