Serotonin Transporter mRNA Expression Is Reduced in the Peripheral Blood Mononuclear Cells of Subjects with Major Depression but Normal in Fibromyalgia.
Gaël Villanueva-CharbonneauStéphane PotvinSerge MarchandAlexander McIntyreDiane McIntoshAlain BissonnetteAlain GendronCharles-Edouard GiguèreMarie-Ève KouéÉdouard KouassiPublished in: Brain sciences (2023)
These results corroborate the role of the SERT in the pathophysiology of MDD, but not in FM, and show that the decreased mRNA expression of SERT is a persistent, rather than transient, phenomenon.