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Serotonin Transporter mRNA Expression Is Reduced in the Peripheral Blood Mononuclear Cells of Subjects with Major Depression but Normal in Fibromyalgia.

Gaël Villanueva-CharbonneauStéphane PotvinSerge MarchandAlexander McIntyreDiane McIntoshAlain BissonnetteAlain GendronCharles-Edouard GiguèreMarie-Ève KouéÉdouard Kouassi
Published in: Brain sciences (2023)
These results corroborate the role of the SERT in the pathophysiology of MDD, but not in FM, and show that the decreased mRNA expression of SERT is a persistent, rather than transient, phenomenon.
Keyphrases
  • major depressive disorder
  • cerebral ischemia
  • brain injury