Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease.

Caroline PassVictoria R Palzkill Jianna Tan Kyoungrae Kim Trace Thome Qingping YangBrian FazzoneScott T RobinsonKerri A O'MalleyFeng YueSalvatore T Scali Scott A Berceli Terence E Ryan

Published in: Circulation research (2023)

This reference single-nuclei RNA-sequencing atlas provides a comprehensive analysis of the cell composition, transcriptional signature, and intercellular communication pathways that are altered in the PAD condition.

Keyphrases

single cell
peripheral artery disease
gene expression
skeletal muscle
transcription factor
oxidative stress
mesenchymal stem cells
heat shock
heat stress