Combined anti-CD20 and mTOR inhibition with factor VIII for immune tolerance induction in hemophilia A patients with refractory inhibitors.
Bhavya S DoshiLeslie J RaffiniLindsey A GeorgePublished in: Journal of thrombosis and haemostasis : JTH (2020)
This regimen may be considered to induce FVIII tolerance in HA patients with refractory inhibitors. Further characterization of the FVIII-specific immune response is necessary to clarify the mechanism of immune tolerance.
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