Chemical characterization and evaluation of antioxidant activity from different cultivars of Cannabis sativa L. of Abruzzo's region.
Sara PalmieriFederico FantiEleonora OlivaEduardo ViterittiManuel SergiAlessia PepeDario CompagnonePublished in: Natural product research (2022)
In this work, the chemical composition and the antioxidant evaluation of the inflorescences from 12 Cannabis sativa L. monoecious cultivars (Carmagnola Lemon CL, Ferimon F, Gran Sasso Kush GSK, Antal A, Carmagnola C, Kompolti K, Futura 75 F75, Villanova V, Tiborzallasi T, Finola FL, Kc Virtus KV and Pineapple P) cultivated at the same condition, were investigated. GC-MS analysis was carried out to evaluate the volatile fraction, while HPLC-MS/MS was used for cannabinoids and polyphenolic compounds. The evaluation of antioxidant activity was carried out using ABTS *+ , Trolox equivalence antioxidant capacity (TEAC), ferric reducing antioxidant property (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH*) assays in vitro. The obtained data, demonstrated that each cultivar has a characteristic chemical profile, with highest antioxidant capacity for CL, F75, GSK and F. Based on the in vitro antioxidant activity the plant extracts can be considered as promising candidates for different applications in food field.
Keyphrases
- ms ms
- oxidative stress
- signaling pathway
- anti inflammatory
- pi k akt
- liquid chromatography tandem mass spectrometry
- high performance liquid chromatography
- electronic health record
- high throughput
- simultaneous determination
- big data
- atomic force microscopy
- magnetic resonance imaging
- mass spectrometry
- machine learning
- high resolution
- climate change
- solid phase extraction
- deep learning
- data analysis
- iron deficiency