Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer.

Anastasia Constantinidou Yiola Marcou Michael S Toss Timothy Simmons Ryan Bernhisel Elisha Hughes Braden Probst Stephanie Meek Eleni Kakouri Georgios Georgiou Ioanna Zouvani Gabriella Savvidou Vanessa Kuhl Jennifer Doedt Susanne Wagner Alexander Gutin Thomas P Slavin Jerry S Lanchbury Ralf Kronenwett Ian O Ellis Emad A Rakha

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

The EPclin score is strongly associated with DRFS in pre-menopausal women who received adjuvant endocrine therapy alone. On the basis of these data, pre-menopausal women with EPclin low-risk breast cancer may be treated with endocrine therapy only and safely forgo adjuvant chemotherapy.

Keyphrases

early stage
polycystic ovary syndrome
breast cancer risk
electronic health record
type diabetes
metabolic syndrome
machine learning
pregnant women
estrogen receptor
newly diagnosed
skeletal muscle
cell therapy
artificial intelligence