Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs).

Jenna Shiels Krystyna CwiklinskiRaquel AlvaradoKarine ThiviergeSophie CottonBibiana Gonzales SantanaJoyce ToSheila DonnellyClifford C TaggartSinéad WeldonJohn P Dalton

Published in: PLoS neglected tropical diseases (2020)

These results offer new insights into the structure and function of a well-known immunomodulatory molecule, Sm16, and places it within a wider family of trematode-specific small molecule HDM immune-modulators with immuno-biotherapeutic possibilities.

Keyphrases

small molecule
protein protein