Interictal blood-brain barrier dysfunction in piriform cortex of people with epilepsy.
Freya SchulteJohannes T ReiterTobias BauerJulia TaubeFelix BitzerJuri-Alexander WittRory J PiperAnoja ThanabalasingamRandi von WredeAttila RaczTobias BaumgartnerValeri BorgerLouisa Specht-RiemenschneiderHartmut VatterElke HattingenRalf DeichmannChristoph HelmstaedterAlexander RadbruchAlon FriedmanRainer SurgesTheodor RuberPublished in: Annals of clinical and translational neurology (2024)
Interictal blood-brain barrier dysfunction occurs in the piriform cortex in temporal lobe epilepsy. This dysfunction is linked to longer disease duration and worse cognitive deficits, emphasizing the central role of the piriform cortex in the epileptogenic network of temporal lobe epilepsy.