Overexpression of hsa_circ_0008274 inhibited the progression of lung adenocarcinoma by regulating HMGA2 via sponging miR-578.

Maolong WangMinge MaYuling YangChuan LiZhaoyang WangXiao SunMengdi WangYong SunWenjie Jiao

Published in: Thoracic cancer (2021)

In summary, our data show that the overexpression of hsa_circ_0008274 repressed the proliferation and invasion of LUAD through downregulating miR-578 and activating HMGA2.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
signaling pathway
transcription factor
big data
machine learning