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Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation.

Kaysan SohrabiHoussein AhmadiAbdollah AminiBehnaz AhrabiAtarodalsadat MostafaviniaHamidreza OmidiMansooreh MirzaeiFatemeh Fadaei FathabadyMohammadjavad FridoniMaryam RahmanniaSufan ChienMohammad Bayat
Published in: Laboratory animal research (2023)
h-ASC-COM + PBM, PBM, and h-ASC-COM cures expressively accelerated the maturation stage in the wound healing process of IIDHWM with MRSA in TIIDM rats by diminishing the inflammatory reaction, and the microbial flora of MRSA; and increasing wound strength, WCR, number of fibroblasts, and new blood vessels. While the h-ASC-COM + PBM and PBM were more suitable than the effect of h-ASC-COM, the results of h-ASC-COM + PBM were superior to PBM only.
Keyphrases
  • wound healing
  • nlrp inflammasome
  • diabetic rats
  • methicillin resistant staphylococcus aureus
  • oxidative stress
  • staphylococcus aureus
  • endothelial cells
  • induced pluripotent stem cells
  • extracellular matrix