Disruption of DNA-PKcs-mediated cGAS retention on damaged chromatin potentiates DNA damage-inducing agent-induced anti-multiple myeloma activity.

Jin-Na ZhangMeng-Meng DongWen CaoHao-Guang ChenHui-Yao GuYi-Li FengEn-Fan ZhangJing-Song HeSi-Cheng LiuAn-Yong XieZhen Cai

Published in: British journal of cancer (2024)

Inhibition of DNA-PKcs could improve the efficacy of doxorubicin in treatment of MM by de-sequestrating cGAS in damaged chromatin.

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