Crosstalk between genetic variability of adiponectin and leptin, glucose-insulin system and subclinical atherosclerosis in patients with newly diagnosed type 2 diabetes. The Verona Newly Diagnosed Type 2 Diabetes Study 14.

Chiara ZusiAlessandro CsermelyElisabetta RinaldiKezia BertoldoSara BonettiMaria Linda BoselliDaniela TraviaEnzo BonoraRiccardo C BonadonnaMaddalena Trombetta

Published in: Diabetes, obesity & metabolism (2023)

Results of this study reinforce knowledge on adipokines' role in regulating glucose metabolism; in particular highlighted the potential atherogenic role of leptin and the anti atherogenic role of adiponectin.

Keyphrases

type diabetes
newly diagnosed
insulin resistance
glycemic control
cardiovascular disease
healthcare
metabolic syndrome
genome wide
blood pressure
gene expression
skeletal muscle
adipose tissue
dna methylation