Design of Multidrug-Resistant Tuberculosis Treatment Regimens Based on DNA Sequencing.

Hans-Peter GrobbelMatthias MerkerNiklas KöhlerSönke AndresHarald HoffmannJan HeyckendorfMaja ReimannIvan BarilarViola DreyerDoris HillemannBarbara KalsdorfThomas A KohlPatricia Sanchez CarballoDagmar SchaubKatharina TodtChristian UtpatelFlorian P MaurerChristoph LangeStefan Niemann

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)

NGS-based genomic DST can reliably guide the design of effective MDR/RR-TB treatment regimens.

Keyphrases

multidrug resistant
mycobacterium tuberculosis
escherichia coli
single cell
acinetobacter baumannii
combination therapy
gram negative
cell free
smoking cessation