The Antibiotic Drug Trimethoprim Suppresses Tumor Growth and Metastasis via Targeting Snail.

Bo-Xue RenYang LiHong-Mei LiTao LuZhao-Qiu WuRong Fu

Published in: British journal of pharmacology (2021)

These findings indicate, for the first time, that trimethoprim suppresses tumor growth and metastasis via targeting Snail. This study provides insights for a better understanding of the anticancer effects of trimethoprim and offers a potential anti-cancer therapeutic agent for clinical treatment.

Keyphrases

epithelial mesenchymal transition
signaling pathway
cancer therapy
emergency department
risk assessment
replacement therapy
adverse drug
smoking cessation